Physical Geology Essay Example | Topics and Well Written Essays - 1750 words

Physical Geology - Essay Example The landscapes we see around us have many different and varying features, many of which have been fashioned by a number of external forces. Erosion is probably the major force in this respect and it can come from a number of sources, such as wind, water and ice. While these sources can be seen to be unique, in fact in the majority of cases they usually combine within the erosion process that shapes our landscapes. Wind is forceful creator of particular land features, especially in areas where deserts exist, normally close to the equator. In this instance as the warm air rises, forming clouds, the winds blow these away from the equator, both north and south, leaving a dryer condition. As a result, these areas receive significantly reduced rainfall, limiting the amount of vegetation, which would bind the earth’s surface together. The wind also carries particles of plants and rocks with it to create a build up of vegetation and chemical deposits in other areas. The power of the w ind, for example in the form of hurricanes, can have a significant effect on the landscape, as well as destroying human habitats.

Bio Essay Example | Topics and Well Written Essays - 500 words

Bio - Essay Example Geology, B.A. Biology where he states that the science involved with ring width measurements currently that show tree rings occur no more than once a year, and as a result this is something that cannot be debated unless you look at possibility of numerous disturbances occurring which could theoretically have changed the chronology. (Woodrappe 2) Unfortunately, this is a hypothesis that others have disproved and that Dawkins himself finds interesting. Unfortunately, the science attempted by the apologetics site is such that it is not provable and is not currently peer reviewed. Another interesting view of tree ring dating is taken by author Bryan Bannister in his paper published in American Antiquity where he states, â€Å"Once a date has been derived, however, its archeological significance may vary widely, since the date can only be applied with authority to the tree itself.† (Bannister 508) Dawkins goes to great lengths to explain that this dating approach is applicable but only when used with other approaches. He does however; explain that by cross-referencing the rings themselves with other trees in the area you can in fact present a much clearer case for age as you will likely have overlaps in the rings creating a potentially unbreakable chain of evidence in dating for some things. (Dawkins, Ph.D. FRS, FRSL) Further in he approaches sedimentary levels and dating using earth strata.

Genetic Mutations Result In Faulty Proteins

Genetic Mutations Result In Faulty Proteins The DNA sequence codes for a particular gene which is then copied into a protein sequence code. Protein is found in every cell in human body and has a vital role in cell growth and tissue repair. The amino acids are the building blocks of proteins which are arranged in a specific order to determine the proteins shape and function. The incorrect amino acid sequence leads to harmful consequences because it can lead to the formation of faulty proteins which can cause disruption in metabolic and regulatory pathways which cause genetic disorders (1). Genetic mutation is a change in genomic sequence which encodes DNA. It can be either inherited or somatic mutation. Somatic mutations are introduced either during DNA replication or when the DNA repair process fails. Agents which damage DNA are frequent carcinogens. Most carcinogenic agents are mutagens. There are two classes of mutations caused by mutagens. The first class is spontaneous mutations caused by depurination, deamination and demethylation(3). The second class is induced mutations caused by ionizing radiation,chemical mutagens and ultra violet radiation(3). Mutation during DNA replication Before cell divides, cell duplicates its entire DNA sequence. To start DNA replication, the DNA helicase separates the DNA molecule into two strands. Then DNA polymerase copies each strand of DNA in order to create two double-stranded DNA molecules. Somatic mutation occurs when this DNA polymerase makes an error in copying which takes place once every 100,000,000 bases (4). Mutation effects Single base substitution: The consequences of single base substitution mutation depend on the location of the protein which can lead to either silent mutation, missense mutation or a non-sense mutation. Silent mutations are those which dont produce any change in an amino acid sequence of a protein. They occur in that region that either doesnt code for a protein or doesnt alter the final sequence of amino acid chain. For example GCA codon turns into GCG codon as in result of single nucleotide replacement because both GCA and GCG codons mean arginine in mRNA (8). Missense mutations involve a change in a single nucleotide to cause substitution of a different amino acid. This can result into a non-functional protein. Sickle cell anemia is an example of missense mutation where CTC in the DNA sense strand specifies glutamate residue get altered with GUG in the mRNA which results in a Valine residue in the protein causing sickle-cell anemia (8). Non-sense mutations are those which results in a premature stop codon leading to the formation of a non-functional protein. An example for non-sense mutation is a single nucleotide replacement from C to T in codon CAG which forms a stop codon TAG. This incorrect sequence causes the shortening of protein (8). Frameshift mutation: This mutation is the result of an insertion or a deletion of one or more nucleotides from the DNA sequence but not in multiples of three because bases in set of three forms a codon which provides the code for an amino acid sequence of the protein. So as DNA polymerase read the triplet nature of codon so an insertion or a deletion can disrupt its reading frame which results into a completely different translation done by the DNA polymerase (8+6). Chromosome mutation: Any change either in structure or arrangement of chromosomes is a chromosome mutation which frequently occurs in meiosis during crossing over. The different types of chromosome mutation are:- Translocation: In this mutation, a piece of one chromosome gets transferred to a non-homologous chromosome. For example when translocation between chromosomes 9 and 22 takes place, an abnormal gene forms which codes for an abnormal faulty protein resulting the development of leukaemia (8). Inversion: During this mutation, a DNA region on a chromosome flips its orientation leading the formation of an abnormal gene which then codes for a faulty abnormal protein. Deletion: In this mutation, a chromosome section gets deleted which results in the loss of genes (6). Duplication: During this mutation, some genes get duplicate and get read twice by the DNA polymerase on the same chromosome resulting in the formation of a faulty abnormal protein (6). Non-disjunction: This is when chromosomes dont separate successfully to opposite poles at anaphase stage during meiosis which allows the presence of an extra chromosome in one of the daughter cells. Downs syndrome is an example of non-disjunction which occurs in chromosome 21 of a human egg cell (8). Removal of faulty proteins In eukaryotic cells, faulty proteins are recognized and degraded very rapidly in cells to prevent any harmful consequences. The two major faulty protein destruction pathways are:- Ubiquitin-proteasome pathway for faulty intracellular proteins: In the case of formation of faulty proteins which are defective get ejected into the proteasome from the endoplasmic reticulum through channels called retrotranslocons. Proteasome is a large multi-catalytic protein complex found in all eukaryotes which is located in nucleus and cytoplasm. It is responsible to degrade faulty intracellular proteins through proteolysis(2). The enzymes which carry out proteolysis are known as proteases. Those intracellular proteins which need to go under degradation get tagged with another small protein called ubiquitin(2). Ubiquitin binds to the amino group of the side chain of a lysine residue. This tagging process is catalyzed by ubiquitin ligase. Once the protein gets tagged,a signal gets released to other ligases allowing more ubiquitin molecules to attach to form a poly-ubiquitin chain. Poly-ubiquitin chain then bound by the 26s proteasome complex which leads to the degradation of tagged protein(7). Ubiquitin does get released which that can be reused in next cycle. However ATP is used for the attachment of ubiquitin and for the degradation of tagged proteins (5). Lysosomal proteolysis for faulty extracellular proteins: Lysosomes are membrane-enclosed cellular organelles in animals containing digestive enzymes and proteases. They have important roles in cell metabolism including the digestion of extracellular proteins taken up through endocytosis. So during this protein degradation pathway, the protein is uptaken by lysosomes through the formation of vesicles derived from endoplasmic reticulum called autophagosomes. Then these autophagosomes fuse with lysosomes so in result the digestive lysosomal enzymes digest their contents (5).

Annual Budget Model Essay -- Business, Traditional Budgeting Model

Introduction Budgeting is a process in which every firm has to be involved with not only the board of director (Principle) who authorize the budget but also management team (Agent) who use it as well. In other words, budgeting need communication with every level of employee in the company in order to construct the goal or strategy of the company. Moreover, budgets are an instrument of power as well as being a reflection of power (Ashton et. al., 1995, p.289). Budgets that are not based on well-understood activities and costs are poor indicators of performance (Drury, 2005). Nowadays, at the time of information and technology the conventional budgeting is not good enough for withstand the rivalry in the global market. As Hope and Fraser, 2000 cited from Young, 2006 say the traditional performance management model cannot reflect today’s discontinuous change economy, which is why they point that annual budget model may be seen as having a number of intrinsic weaknesses and acting as a barrier to the effective implementation of alternative models for utilize in the success of strategic change. Therefore, I separate my essay into two parts. First, indicate and criticize on five inbred weaknesses of annual budget model. Second, explain ways in which the conventional budgeting process may be seen as an obstacle to accomplishment of the aims of Benchmarking, Balanced scorecard, and Activity-based models for the fulfillment of strategic change. Discuss on inherent weakness of annual budget model There are many weaknesses of traditional budgeting model and it has been the matter of considerable caviling. From recently research by Libby and Linsay, 2010 cited from Hansen et. al., 2003 encapsulated several discussions of budgets an... ...vities are prepared on an incremental basis or called incremental budgeting. This means that running operations and the current budgeted allowance for existing activities are taken as the starting point for preparing the next annual budget. The base is then adjusting for changes such as changes in product mix, volumes, and price that are expected to occur during the new budget period. For example, the allowance for budgeted expenses may be based on the previous budgeted allowance plus an increase to cover higher prices caused by inflation The major disadvantage of incremental approach is that the majority of expenditure, which is associated with the ‘base level’ of activity, remains unchanged. Therefore, the costs of non-unit level activities become fixed and past inefficiencies and waste inherent in the current way of doing things is perpetuated (Drury, 2005).

Profit

1. a. The total explicit cost is $793,000($970,000-$177,000). The total implicit cost is $190,000($175,000+. 15X$100,000). The total economic costs is $983,000($793,000+$190,000). b. The accounting profit in 2010 is $177,000($970,000-$793,000) c. The economic profit in 2010 is $-13,000($970,000-$793,000-$190,000). d. The owner should not leave his job because the economic profit is negative, which means he will earn less if he does his own business. 2. a.The type of agency problem that is involved here is principal-agent problem. Marriott wants to maintain a certain level of quality at all of its hotels, but in order to do that it would require capital investment by franchisees. By investing in the hotels, the franchisees are losing profits. b. I believe that Marriott needs to worry about the quality of all the hotels whether they are owned or franchised. In order to keep customers satisfied and coming back to stay at a Marriott they need to keep a good reputation. c.Marriott would t end to own its hotels in resort areas because the people will be more focused on the quality and upkeep of the hotel itself. By Marriott providing good quality in resort areas it will help them gain more business in downtown areas due to the customers’ previous experience. In downtown areas it is also more difficult to find a high quality hotel. If people do not have a good experience at a Marriott then the next time they need to stay in a hotel they will travel further down the street to a different hotel due to the poor quality of the previous Marriott stay.The reputation of the Marriott depends highly on how much business it will have. A good reputation will lead to great profits. 3. a. I would expect the price of wine to decrease as well. b. I would expect the price of wine to decrease because the quantity demanded for wine will increase. c. I would expect the price of wine to decrease as well because the quantity demanded will increase due to people having a job and maki ng more money. d. I would expect the price of wine to decrease.A rise in the price of cheese will decrease demand for cheese, which should decrease demand for wine which in turn will decrease the price for wine. e. I would expect the price of wine to increase due to the increase in prices of the wine bottles. f. I would expect the price of wine to decrease since it will be cheaper to produce. g. I would expect the price of wine to decrease. h. Since older people drink less wine, demand would be falling in this case. As a result, the price would decrease. 4. a. 5.I believe that the equilibrium price of products gaining a presence on the Internet will increase because the quantity demanded will be higher and the equilibrium output will also increase. Since it will be new to the internet the demand will increase which will make the price increase as well. 6. MC=MR 1000-10P=40P 50P=1000 P= 1000/50 P=20 units (reduction of pollution units) 7. a. MB=MC MC is w=200 and MB from hiring a sec ond worker is MB(2)=(30-20)X25=250 TB=(50-20)X25-(200X2)=750-400=350 The firm will hire two guards. b.The benefit from the first guard is: B(1)=(50-30)X25=20X25=500. The maximum payment to the first guard the firm will be willing to pay is $500. c. MC=200 MB(4)=(14-8)x50=6X50=300 TB=(50-8)X50-(4X200)=1300 Therefore the firm should hire 4 guards. 8. a. Price=MC 70=40+0. 005Q; Q=6000 The MR for each unit of output is the same at $70. b. TR=70X6000=$420,000 TC=10,000+(40X6000)+(0. 0025X(6000)^2)=$340,000 Total Profits=$420,000-$340,000=$80,000 c. MR=MC therefore providing one more unit of output will earn $70 and cost $70 so there would be no profit.

Driving a car or riding a motorcycle? Essay

Transportations take us to anywhere we want to go and make our life easier. Without them, we will feel like losing our feet. Cars and motorcycles are inventions for people to travel faster. They both have their supporters based on their conveniences, safeties, and expenses. First, both cars and bikes are convenient for people to travel around. They both have some kind of way of controlling the direction of travel. Motorcycles can get to the short destinations and find a parking quickly and easily. As long distance, cars have many accessories such as radio, CD players, navigational systems, and even TVs. Let riders killing times while long driving. Second, safety can be concerned since many dangerous accidents are reported. The car has a roof and windows to keep you from all kinds of weather. Moreover, seatbelts and airbags in a car are able to protect passengers form an accident. Unlike more and more accidents caused by checking phones, motorcycle riders don’t text on their phones while riding. They will not be distracted by food or coffee, either. The last important key element to choose between cars and bikes is expense. Motorcycles cost less. Even work-study students can afford it. In addition, bikes use less gas. 30 miles per gallon is on the low end and smaller engines can get triple digit mileage. On the other hand, when getting a car, there are a lot of choices according to the budget. If you are lucky, you can still get a fancy one with a good price. Cars and motorcycles make people travel faster. Some people like motorcycles over cars and some people prefer cars over motorcycles, depending on their conveniences, safeties, and expenses. There are still many other differences between cars and motorcycles. It is better to take some time to find out what you need before making a decision. Careful consideration of the information presented here will have much fun when driving or riding a car or a bike.